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Fine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand

GD3, a ganglioside expressed on melanoma, is the only tumour-associated glycolipid described to date that can induce a CD1d-restricted natural killer T (NKT)-cell response. We analysed the fine specificity of GD3-reactive NKT cells and discovered that immunization with GD3 induced two populations of...

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Detalhes bibliográficos
Main Authors: Park, Jun-Eui, Wu, Dianna Y, Prendes, Maria, Lu, Sharon X, Ragupathi, Govind, Schrantz, Nicolas, Chapman, Paul B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2433273/
https://ncbi.nlm.nih.gov/pubmed/18154620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02760.x
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