β-Galactosylceramide Alters Invariant Natural Killer T Cell Function and is Effective Treatment for Lupus

NZB/W female mice spontaneously develop systemic lupus, an autoantibody mediated disease associated with immune complex glomerulonephritis. Natural Killer (NK) T cells augment anti-dsDNA antibody secretion by NZB/W B cells in vitro, and blocking NKT cell activation in vivo with anti-CD1 mAb ameliora...

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Hlavní autoři: Morshed, Sufi R., Takahashi, Tsuyoshi, Savage, Paul B., Kambham, Neeraja, Strober, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720447/
https://ncbi.nlm.nih.gov/pubmed/19564135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.05.018
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