Invariant Natural Killer T cells in lupus patients promote IgG and IgG autoantibody production

IgG autoantibodies, including antibodies to double-stranded DNA (dsDNA), are pathogenic in systemic lupus erythematosus, but the mechanisms controlling their production are not understood. To assess the role of invariant natural killer T (iNKT) cells in this process, we studied 44 lupus patients. We...

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Foilsithe in:Eur J Immunol
Main Authors: Shen, Lei, Zhang, Hong, Caimol, Maria, Benike, Claudia J., Chakravarty, Eliza F., Strober, Samuel, Engleman, Edgar G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324163/
https://ncbi.nlm.nih.gov/pubmed/25352488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444760
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