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Natural killer T cells and innate immune B cells from lupus-prone NZB/W mice interact to generate IgM and IgG autoantibodies

Lupus-prone NZB/W F1 mice develop glomerulonephritis after T helper cell dependent isotype switching of autoantibody secretion from IgM to IgG at about six months of age. We compared innate immune natural killer (NK) T cells and conventional T cells for their capacity to help spontaneous in vitro im...

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Detalhes bibliográficos
Main Authors: Takahashi, Tsuyoshi, Strober, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915938/
https://ncbi.nlm.nih.gov/pubmed/18050273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737656
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