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Effects of DNA gyrase inhibitors in Escherichia coli topoisomerase I mutants.

Relaxation of titratable supercoils in bacterial nucleoids was measured following treatment of topA mutants with coumermycin or oxolinic acid, inhibitors of DNA gyrase. Relaxation occurred after treatment of the mutants with either inhibitor. We detected no significant difference in relaxation betwe...

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Detalhes bibliográficos
Main Authors: Pruss, G J, Franco, R J, Chevalier, S G, Manes, S H, Drlica, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213448/
https://ncbi.nlm.nih.gov/pubmed/3019999
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