Rifampin and rpoB mutations can alter DNA supercoiling in Escherichia coli.
Two cases are described which indicate that RNA polymerase could alter DNA supercoiling. One occurred in a topA mutant in which abnormally high levels of plasmid supercoiling were lowered by rifampin, an inhibitor of the beta subunit of RNA polymerase. The second case involves suppression of a tempe...
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| Publicado no: | J Bacteriol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC211554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2844734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.170.10.4983-4985.1988 |
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