Rifampin and rpoB mutations can alter DNA supercoiling in Escherichia coli.
Two cases are described which indicate that RNA polymerase could alter DNA supercoiling. One occurred in a topA mutant in which abnormally high levels of plasmid supercoiling were lowered by rifampin, an inhibitor of the beta subunit of RNA polymerase. The second case involves suppression of a tempe...
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| Опубликовано в:: | J Bacteriol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1988
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC211554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2844734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.170.10.4983-4985.1988 |
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