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Effects of DNA gyrase inhibitors in Escherichia coli topoisomerase I mutants.

Relaxation of titratable supercoils in bacterial nucleoids was measured following treatment of topA mutants with coumermycin or oxolinic acid, inhibitors of DNA gyrase. Relaxation occurred after treatment of the mutants with either inhibitor. We detected no significant difference in relaxation betwe...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Pruss, G J, Franco, R J, Chevalier, S G, Manes, S H, Drlica, K
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213448/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3019999/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.168.1.276-282.1986
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