Inhibition of RNA synthesis by oxolinic acid is unrelated to average DNA supercoiling.

Oxolinic acid reduced RNA synthesis rates whether chromosome supercoiling decreased, increased, or remained unchanged. Thus, inhibition of RNA synthesis by oxolinic acid appears to involve factors other than average DNA supercoiling level. Coumermycin A1 caused RNA synthesis rates to increase or dec...

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Bibliografiske detaljer
Main Authors: Manes, S H, Pruss, G J, Drlica, K
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC217697/
https://ncbi.nlm.nih.gov/pubmed/6345510
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