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Distinct Roles for the p110α and hVPS34 Phosphatidylinositol 3′-Kinases in Vesicular Trafficking, Regulation of the Actin Cytoskeleton, and Mitogenesis

We have examined the roles of the p85/ p110α and hVPS34 phosphatidylinositol (PI) 3′-kinases in cellular signaling using inhibitory isoform-specific antibodies. We raised anti-hVPS34 and anti-p110α antibodies that specifically inhibit recombinant hVPS34 and p110α, respectively, in vitro. We used the...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Siddhanta, Uma, McIlroy, James, Shah, Amishi, Zhang, Yitao, Backer, Jonathan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132989/
https://ncbi.nlm.nih.gov/pubmed/9852157
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