Transition from Caspase-dependent to Caspase-independent Mechanisms at the Onset of Apoptotic Execution

We have compared cytoplasmic extracts from chicken DU249 cells at various stages along the apoptotic pathway. Extracts from morphologically normal “committed stage” cells induce apoptotic morphology and DNA cleavage in substrate nuclei but require ongoing caspase activity to do so. In contrast, extr...

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Hauptverfasser: Samejima, Kumiko, Toné, Shigenobu, Kottke, Timothy J., Enari, Masato, Sakahira, Hideki, Cooke, Carol A., Durrieu, Françoise, Martins, Luis M., Nagata, Shigekazu, Kaufmann, Scott H., Earnshaw, William C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132820/
https://ncbi.nlm.nih.gov/pubmed/9763434
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