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Genetic Analysis of the Short Splice Variant of the Inhibitor of Caspase-activated DNase (ICAD-S) in Chicken DT40 Cells*

We have studied the regulation of the caspase-Activated DNase (CAD) by its inhibitor, ICAD. To study the role of ICAD short and long splice forms ICAD-S and ICAD-L, respectively, in vivo, we constructed chicken DT40 cell lines in which the entire coding regions of ICAD alone or ICAD plus CAD were de...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Ageichik, Alexander V., Samejima, Kumiko, Kaufmann, Scott H., Earnshaw, William C.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115951/
https://ncbi.nlm.nih.gov/pubmed/17616520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704307200
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