An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes
CAD (caspase-activated DNase) can cause DNA fragmentation in apoptotic cells. Transgenic mice that ubiquitously express a caspase-resistant form of the CAD inhibitor (ICAD) were generated. Thymocytes prepared from the mice were resistant to DNA fragmentation induced by a variety of stimuli. However,...
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| 發表在: | Genes Dev |
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| Principais autores: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716943/ |
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