An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes

CAD (caspase-activated DNase) can cause DNA fragmentation in apoptotic cells. Transgenic mice that ubiquitously express a caspase-resistant form of the CAD inhibitor (ICAD) were generated. Thymocytes prepared from the mice were resistant to DNA fragmentation induced by a variety of stimuli. However,...

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Bibliographic Details

Published in:	Genes Dev
Main Authors:	McIlroy, Dorian, Tanaka, Masato, Sakahira, Hideki, Fukuyama, Hidehiro, Suzuki, Misao, Yamamura, Ken-ichi, Ohsawa, Yoshiyuki, Uchiyama, Yasuo, Nagata, Shigekazu
Format:	Artigo
Language:	Inglês
Published:	Cold Spring Harbor Laboratory Press 2000
Subjects:	Research Paper
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716943/
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