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The antibacterial arm of the Drosophila innate immune response requires an IκB kinase

The ird5 gene was identified in a genetic screen for Drosophila immune response mutants. Mutations in ird5 prevent induction of six antibacterial peptide genes in response to infection but do not affect the induction of an antifungal peptide gene. Consistent with this finding, Escherichia coli survi...

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Autori principali: Lu, Yiran, Wu, Louisa P., Anderson, Kathryn V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC312606/
https://ncbi.nlm.nih.gov/pubmed/11156609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.856901
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