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The antibacterial arm of the Drosophila innate immune response requires an IκB kinase

The ird5 gene was identified in a genetic screen for Drosophila immune response mutants. Mutations in ird5 prevent induction of six antibacterial peptide genes in response to infection but do not affect the induction of an antifungal peptide gene. Consistent with this finding, Escherichia coli survi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Lu, Yiran, Wu, Louisa P., Anderson, Kathryn V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312606/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11156609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.856901
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