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Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter
Cocaine and other psychostimulants act by blocking the dopamine transporter. Binding of the cocaine analog, [(3)H]2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane (CFT) to the dopamine transporter is sensitive to polar sulfhydryl-specific derivatives of methanethiosulfonate (MTS). These reagents prefer...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21322/ https://ncbi.nlm.nih.gov/pubmed/9689064 |
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