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Peroxynitrite Inactivates the Human Dopamine Transporter by Modification of Cysteine 342: Potential Mechanism of Neurotoxicity in Dopamine Neurons
Peroxynitrite (ONOO(−)) has been implicated as a causative factor in dopamine neuronal damage resulting from exposure to methamphetamine and1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), and it may be involved in the etiology of Parkinson's Disease. ONOO(−) causes a concentration-dependen...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6758823/ https://ncbi.nlm.nih.gov/pubmed/12040046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-11-04399.2002 |
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