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β-Lactam synthetase: A new biosynthetic enzyme
The principal cause of bacterial resistance to penicillin and other β-lactam antibiotics is the acquisition of plasmid-encoded β-lactamases, enzymes that catalyze hydrolysis of the β-lactam bond and render these antibiotics inactive. Clavulanic acid is a potent inhibitor of β-lactamases and has prov...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The National Academy of Sciences
1998
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21295/ https://ncbi.nlm.nih.gov/pubmed/9689037 |
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