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The catalytic cycle of β-lactam synthetase observed by x-ray crystallographic snapshots
The catalytic cycle of the ATP/Mg(2+)-dependent enzyme β-lactam synthetase (β-LS) from Streptomyces clavuligerus has been observed through a series of x-ray crystallographic snapshots. Chemistry is initiated by the ordered binding of ATP/Mg(2+) and N(2)-(carboxyethyl)-l-arginine (CEA) to the apoenzy...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137491/ https://ncbi.nlm.nih.gov/pubmed/12409610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232361199 |
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