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Convergent biosynthetic pathways to β-lactam antibiotics
Five naturally-occurring β-lactams have inspired a class of drugs that constitute >60% of the antimicrobials used in human medicine. Their biosynthetic pathways reveal highly individualized synthetic strategies that yet converge on a common azetidinone ring assembled in structural contexts that c...
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| Published in: | Curr Opin Chem Biol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161666/ https://ncbi.nlm.nih.gov/pubmed/27693891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.09.013 |
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