Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link,

Proteins that discriminate between cisplatin–DNA adducts and oxaliplatin–DNA adducts are thought to be responsible for the differences in tumor range, toxicity, and mutagenicity of these two important chemotherapeutic agents. However, the structural basis for differential protein recognition of thes...

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Bibliografiska uppgifter
Huvudupphovsmän: Wu, Yibing, Bhattacharyya, Debadeep, King, Candice L., Baskerville-Abraham, Irene, Huh, Sung-Ho, Boysen, Gunnar, Swenberg, James A., Temple, Brenda, Campbell, Sharon L., Chaney, Stephen G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2129171/
https://ncbi.nlm.nih.gov/pubmed/17497831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062291f
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