Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1

Recent studies indicate that the LKB1 is a key regulator of the AMP-activated protein kinase (AMPK), which plays a crucial role in protecting cardiac muscle from damage during ischemia. We have employed mice that lack LKB1 in cardiac and skeletal muscle and studied how this affected the activity of...

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Detalhes bibliográficos
Main Authors: Sakamoto, Kei, Zarrinpashneh, Elham, Budas, Grant R., Pouleur, Anne-Catherine, Dutta, Anindya, Prescott, Alan R., Vanoverschelde, Jean-Louis, Ashworth, Alan, Jovanović, Aleksandar, Alessi, Dario R., Bertrand, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128705/
https://ncbi.nlm.nih.gov/pubmed/16332922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00443.2005
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