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Importance of group X–secreted phospholipase A(2) in allergen-induced airway inflammation and remodeling in a mouse asthma model
Arachidonic acid metabolites, the eicosanoids, are key mediators of allergen-induced airway inflammation and remodeling in asthma. The availability of free arachidonate in cells for subsequent eicosanoid biosynthesis is controlled by phospholipase A(2)s (PLA(2)s), most notably cytosolic PLA(2)-α. 10...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118555/ https://ncbi.nlm.nih.gov/pubmed/17403936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070029 |
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