Adjuvanting a DNA vaccine with a TLR9 ligand plus Flt3 ligand results in enhanced cellular immunity against the simian immunodeficiency virus

DNA vaccines offer promising strategies for immunization against infections. However, their clinical use requires improvements in immunogenicity. We explored the efficacy of Toll-like receptor (TLR) ligands (TLR-Ls) on augmenting the immunogenicity of a DNA prime–modified vaccinia virus Ankara (MVA)...

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Bibliographische Detailangaben
Hauptverfasser: Kwissa, Marcin, Amara, Rama R., Robinson, Harriet L., Moss, Bernard, Alkan, Sefik, Jabbar, Abdul, Villinger, Francois, Pulendran, Bali
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118478/
https://ncbi.nlm.nih.gov/pubmed/17954572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071211
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