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Prevention of Peripheral Tolerance by a Dendritic Cell Growth Factor: Flt3 Ligand as an Adjuvant

Injections of soluble proteins are poorly immunogenic, and often elicit antigen-specific tolerance. The mechanism of this phenomenon has been an enduring puzzle, but it has been speculated that tolerance induction may be due to antigen presentation by poorly stimulatory, resting B cells, which lack...

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Detalhes bibliográficos
Main Authors: Pulendran, Bali, Smith, J.L., Jenkins, M., Schoenborn, M., Maraskovsky, E., Maliszewski, C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212387/
https://ncbi.nlm.nih.gov/pubmed/9841921
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