IL-25 regulates Th17 function in autoimmune inflammation

Interleukin (IL)-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. We now show that IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells. We have generated IL-25–...

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Main Authors: Kleinschek, Melanie A., Owyang, Alexander M., Joyce-Shaikh, Barbara, Langrish, Claire L., Chen, Yi, Gorman, Daniel M., Blumenschein, Wendy M., McClanahan, Terrill, Brombacher, Frank, Hurst, Stephen D., Kastelein, Robert A., Cua, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118427/
https://ncbi.nlm.nih.gov/pubmed/17200411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061738
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