IL-25 elicits a multi-potent progenitor cell population that promotes Th2 cytokine responses

gan Saenz, Steven A., Siracusa, Mark C., Perrigoue, Jacqueline G., Spencer, Sean P., Urban, Joseph F., Tocker, Joel E., Budelsky, Alison L., Kleinschek, Melanie A., Kastelein, Robert A., Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Cyhoeddwyd 2010

IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

gan Yen, David, Cheung, Jeanne, Scheerens, Heleen, Poulet, Frédérique, McClanahan, Terrill, Mckenzie, Brent, Kleinschek, Melanie A., Owyang, Alex, Mattson, Jeanine, Blumenschein, Wendy, Murphy, Erin, Sathe, Manjiri, Cua, Daniel J., Kastelein, Robert A., Rennick, Donna
Cyhoeddwyd 2006

IL-25 regulates Th17 function in autoimmune inflammation

gan Kleinschek, Melanie A., Owyang, Alexander M., Joyce-Shaikh, Barbara, Langrish, Claire L., Chen, Yi, Gorman, Daniel M., Blumenschein, Wendy M., McClanahan, Terrill, Brombacher, Frank, Hurst, Stephen D., Kastelein, Robert A., Cua, Daniel J.
Cyhoeddwyd 2007

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

gan Kleinschek, Melanie A., Boniface, Katia, Sadekova, Svetlana, Grein, Jeff, Murphy, Erin E., Turner, Scott P., Raskin, Lisa, Desai, Bela, Faubion, William A., de Waal Malefyt, Rene, Pierce, Robert H., McClanahan, Terrill, Kastelein, Robert A.
Cyhoeddwyd 2009

Development of Gut-Selective Pan-Janus Kinase Inhibitor TD-1473 for Ulcerative Colitis: A Translational Medicine Programme

gan Sandborn, William J, Nguyen, Deanna D, Beattie, David T, Brassil, Patrick, Krey, Whitney, Woo, Jacky, Situ, Eva, Sana, Reuben, Sandvik, Erik, Pulido-Rios, M Teresa, Bhandari, Raj, Leighton, Jonathan A, Ganeshappa, Ravi, Boyle, David L, Abhyankar, Brihad, Kleinschek, Melanie A, Graham, Richard A, Panes, Julian
Cyhoeddwyd yn J Crohns Colitis (2020)

Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4

gan Lim, Jongwon, Altman, Michael D., Baker, James, Brubaker, Jason D., Chen, Hongmin, Chen, Yiping, Fischmann, Thierry, Gibeau, Craig, Kleinschek, Melanie A., Leccese, Erica, Lesburg, Charles, Maclean, John K. F., Moy, Lily Y., Mulrooney, Erin F., Presland, Jeremy, Rakhilina, Larissa, Smith, Graham F., Steinhuebel, Dietrich, Yang, Ruojing
Cyhoeddwyd yn ACS Med Chem Lett (2015)

A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system

gan St. Pierre, Cristina, Guo, Jane, Shin, John D., Engstrom, Laura W., Lee, Hyun-Hee, Herbert, Alan, Surdi, Laura, Baker, James, Salmon, Michael, Shah, Sanjiv, Ellis, J. Michael, Houshyar, Hani, Crackower, Michael A., Kleinschek, Melanie A., Jones, Dallas C., Hicks, Alexandra, Zaller, Dennis M., Alves, Stephen E., Ramadas, Ravisankar A.
Cyhoeddwyd yn PLoS One (2017)