A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system

While the immune system is essential for the maintenance of the homeostasis, health and survival of humans, aberrant immune responses can lead to chronic inflammatory and autoimmune disorders. Pharmacological modulation of drug targets in the immune system to ameliorate disease also carry a risk of...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS One
المؤلفون الرئيسيون: St. Pierre, Cristina, Guo, Jane, Shin, John D., Engstrom, Laura W., Lee, Hyun-Hee, Herbert, Alan, Surdi, Laura, Baker, James, Salmon, Michael, Shah, Sanjiv, Ellis, J. Michael, Houshyar, Hani, Crackower, Michael A., Kleinschek, Melanie A., Jones, Dallas C., Hicks, Alexandra, Zaller, Dennis M., Alves, Stephen E., Ramadas, Ravisankar A.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2017
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515432/
https://ncbi.nlm.nih.gov/pubmed/28719615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180870
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