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Role of HMGB1 in apoptosis-mediated sepsis lethality

Severe sepsis, a lethal syndrome after infection or injury, is the third leading cause of mortality in the United States. The pathogenesis of severe sepsis is characterized by organ damage and accumulation of apoptotic lymphocytes in the spleen, thymus, and other organs. To examine the potential cau...

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Detalhes bibliográficos
Main Authors: Qin, Shixin, Wang, Haichao, Yuan, Renqi, Li, Hui, Ochani, Mahendar, Ochani, Kanta, Rosas-Ballina, Mauricio, Czura, Chris J., Huston, Jared M., Miller, Ed, Lin, Xinchun, Sherry, Barbara, Kumar, Anjali, LaRosa, Greg, Newman, Walter, Tracey, Kevin J., Yang, Huan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118346/
https://ncbi.nlm.nih.gov/pubmed/16818669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052203
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