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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation
B cells responding to T-dependent antigen either differentiate rapidly into extrafollicular plasma cells or enter germinal centers and undergo somatic hypermutation and affinity maturation. However, the physiological cues that direct B cell differentiation down one pathway versus the other are unkno...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118299/ https://ncbi.nlm.nih.gov/pubmed/16606676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060087 |
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