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Germinal Center and Extrafollicular B Cell Responses in vaccination, immunity and autoimmunity

Activated B cells participate in either extrafollicular (EF) or germinal center (GC) responses. Canonical responses are composed of a short wave of unmutated plasma cells arising from EF sites, followed by GC producing somatically mutated memory B cells (MBC) and long-lived plasma cells. However, so...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Elsner, Rebecca A., Shlomchik, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748291/
https://ncbi.nlm.nih.gov/pubmed/33326765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.11.006
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