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IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression

Germinal centers (GC) are crucial for the formation of long-lived humoral immunity. Many pathogens suppress GC, including Salmonella enterica serovar Typhimurium (STm), but the mechanisms driving suppression remain unknown. We report that neither plasmablasts nor STm-specific B cells are required fo...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Elsner, Rebecca A., Shlomchik, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908568/
https://ncbi.nlm.nih.gov/pubmed/31775046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.069
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