Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB

Rheumatoid arthritis (RA) is a complex autoimmune disease with a poorly understood pathogenesis. The disease is associated with polyclonal B cell activation and the production of autoantibodies (autoAbs), but there is a longstanding controversy as to whether such Abs contribute to, or are secondary...

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Detalhes bibliográficos
Main Authors: Petkova, Stefka B., Konstantinov, Konstantin N., Sproule, Thomas J., Lyons, Bonnie L., Awwami, Moheeb Al, Roopenian, Derry C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118221/
https://ncbi.nlm.nih.gov/pubmed/16476768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051951
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