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Genetic polymorphism of the inhibitory IgG Fc receptor FcγRIIb is not associated with clinical outcome in patients with follicular lymphoma treated with rituximab

Polymorphisms of activating FcγRIIIa (CD16) and FcγRIIa (CD32a) have been found to predict rituximab response, probably because of the relative efficiency of different FcγR variants in performing antibody-dependent cellular cytotoxicity. The inhibitory FcγRIIb (CD32b) has an opposing effect on effec...

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Detalhes bibliográficos
Main Authors: WENG, WEN-KAI, LEVY, RONALD
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910394/
https://ncbi.nlm.nih.gov/pubmed/19452316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190902829441
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