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Genetic polymorphism of the inhibitory IgG Fc receptor FcγRIIb is not associated with clinical outcome in patients with follicular lymphoma treated with rituximab

Polymorphisms of activating FcγRIIIa (CD16) and FcγRIIa (CD32a) have been found to predict rituximab response, probably because of the relative efficiency of different FcγR variants in performing antibody-dependent cellular cytotoxicity. The inhibitory FcγRIIb (CD32b) has an opposing effect on effec...

詳細記述

保存先:
書誌詳細
主要な著者: WENG, WEN-KAI, LEVY, RONALD
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910394/
https://ncbi.nlm.nih.gov/pubmed/19452316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190902829441
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