Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

The programmed death (PD)-1–PD-1 ligand (PD-L) pathway, which is part of the B7–CD28 family, consists of the PD-1 receptor and its two ligands PD-L1 and PD-L2. Engagement of PD-1 by its ligands inhibits immune responses, and recent work has shown that PD-1 is highly expressed on exhausted T cells du...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Freeman, Gordon J., Wherry, E. John, Ahmed, Rafi, Sharpe, Arlene H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2006
Gaiak:
Commentaries
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118103/
https://ncbi.nlm.nih.gov/pubmed/17000870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061800
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak