Persistent expression of autoantibodies in SLE patients in remission

A majority of the antibodies expressed by nascent B cells in healthy humans are self-reactive, but most of these antibodies are removed from the repertoire during B cell development. In contrast, untreated systemic lupus erythematosus (SLE) patients fail to remove many of the self-reactive and polyr...

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Detalhes bibliográficos
Main Authors: Yurasov, Sergey, Tiller, Thomas, Tsuiji, Makoto, Velinzon, Klara, Pascual, Virginia, Wardemann, Hedda, Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118096/
https://ncbi.nlm.nih.gov/pubmed/16966430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061446
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