Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

The treatment of ischemic strokes is limited to prophylactic agents that block the coagulation cascade. Here, we show that cholesterol-lowering agents, 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors, protect against cerebral injury by a previously unidentified mechanism involving the sele...

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Autores principales: Endres, Matthias, Laufs, Ulrich, Huang, Zhihong, Nakamura, Tadashi, Huang, Paul, Moskowitz, Michael A., Liao, James K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1998
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC21171/
https://ncbi.nlm.nih.gov/pubmed/9671773
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