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A second major native von Hippel–Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor

The von Hippel–Lindau (VHL) tumor suppressor gene is inactivated in both sporadic and inherited clear cell renal carcinoma associated with VHL disease. We have identified two distinct native products of the human VHL gene, with apparent molecular masses of 24 and 18 kDa. The 18-kDa VHL protein was m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schoenfeld, Alan, Davidowitz, Eliot J., Burk, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8817
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