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A second major native von Hippel–Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor

The von Hippel–Lindau (VHL) tumor suppressor gene is inactivated in both sporadic and inherited clear cell renal carcinoma associated with VHL disease. We have identified two distinct native products of the human VHL gene, with apparent molecular masses of 24 and 18 kDa. The 18-kDa VHL protein was m...

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Autors principals: Schoenfeld, Alan, Davidowitz, Eliot J., Burk, Robert D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21160/
https://ncbi.nlm.nih.gov/pubmed/9671762
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