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Vascular tumors in livers with targeted inactivation of the von Hippel–Lindau tumor suppressor

von Hippel–Lindau (VHL) disease is a pleomorphic familial tumor syndrome that is characterized by the development of highly vascularized tumors. Homozygous disruption of the VHL gene in mice results in embryonic lethality. To investigate VHL function in the adult we have generated a conditional VHL...

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Detalhes bibliográficos
Main Authors: Haase, Volker H., Glickman, Jonathan N., Socolovsky, Merav, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29300/
https://ncbi.nlm.nih.gov/pubmed/11171994
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