Vascular tumors in livers with targeted inactivation of the von Hippel–Lindau tumor suppressor

von Hippel–Lindau (VHL) disease is a pleomorphic familial tumor syndrome that is characterized by the development of highly vascularized tumors. Homozygous disruption of the VHL gene in mice results in embryonic lethality. To investigate VHL function in the adult we have generated a conditional VHL...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Haase, Volker H., Glickman, Jonathan N., Socolovsky, Merav, Jaenisch, Rudolf
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2001
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1583
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