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Patented small molecule inhibitors in the ubiquitin proteasome system

Deregulation of the ubiquitin proteasome system (UPS) has been implicated in the pathogenesis of many human diseases, including cancer and neurodegenerative disorders. The recent approval of the proteasome inhibitor Velcade(®) (bortezomib) for the treatment of multiple myeloma and mantle cell lympho...

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Podrobná bibliografie
Hlavní autoři: Guédat, Philippe, Colland, Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106365/
https://ncbi.nlm.nih.gov/pubmed/18047738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-8-S1-S14
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