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Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases

The 26S proteasome is the principal protease for regulated intracellular proteolysis. This multi-subunit complex is also pivotal for clearance of harmful proteins that are produced throughout the lifetime of eukaryotes. Recent structural and kinetic studies have revealed a multitude of conformationa...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Moon, Seonghyeon, Muniyappan, Srinivasan, Lee, Sung-Bae, Lee, Byung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226605/
https://ncbi.nlm.nih.gov/pubmed/34207520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126213
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