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Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors

SIMPLE SUMMARY: The ubiquitin-proteasome system regulates multiple facets of protein homeostasis to modulate signal transduction in numerous biological processes. Not surprisingly, dysregulation of this delicately balanced system is frequently observed in cancer progression. In the past two decades,...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: LaPlante, Gabriel, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235664/
https://ncbi.nlm.nih.gov/pubmed/34203106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13123079
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