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Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors

SIMPLE SUMMARY: The ubiquitin-proteasome system regulates multiple facets of protein homeostasis to modulate signal transduction in numerous biological processes. Not surprisingly, dysregulation of this delicately balanced system is frequently observed in cancer progression. In the past two decades,...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: LaPlante, Gabriel, Zhang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235664/
https://ncbi.nlm.nih.gov/pubmed/34203106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13123079
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