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The proteasome ubiquitin system as a drug target in cerebrovascular disease: The therapeutic potential of proteasome inhibitors
Proteasomes are large multi-catalytic protease complexes that are found in the cytosol and in the nucleus of eukaryotic cells with a central role in cellular protein turnover. The ubiquitin-proteasome system (UPS) is the predominant non-lysosomal protein degradation pathway that ensures the viabilit...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880390/ https://ncbi.nlm.nih.gov/pubmed/16044664 |
| Oznake: |
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