Chargement en cours...
Biogenesis of γ-secretase early in the secretory pathway
γ-Secretase is responsible for proteolytic maturation of signaling and cell surface proteins, including amyloid precursor protein (APP). Abnormal processing of APP by γ-secretase produces a fragment, Aβ(42), that may be responsible for Alzheimer's disease (AD). The biogenesis and trafficking of...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2099203/ https://ncbi.nlm.nih.gov/pubmed/18056412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709012 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|