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Spatial Segregation of γ-Secretase and Substrates in Distinct Membrane Domains

γ-Secretase facilitates the regulated intramembrane proteolysis of select type I membrane proteins that play diverse physiological roles in multiple cell types and tissue. In this study, we used biochemical approaches to examine the distribution of amyloid precursor protein (APP) and several additio...

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書誌詳細
主要な著者: Vetrivel, Kulandaivelu S., Cheng, Haipeng, Kim, Seong-Hun, Chen, Ying, Barnes, Natalie Y., Parent, Ange‘le T., Sisodia, Sangram S., Thinakaran, Gopal
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201532/
https://ncbi.nlm.nih.gov/pubmed/15886206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M503570200
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