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Synaptotagmin C2A Loop 2 Mediates Ca(2+)-dependent SNARE Interactions Essential for Ca(2+)-triggered Vesicle Exocytosis

Synaptotagmins contain tandem C2 domains and function as Ca(2+) sensors for vesicle exocytosis but the mechanism for coupling Ca(2+) rises to membrane fusion remains undefined. Synaptotagmins bind SNAREs, essential components of the membrane fusion machinery, but the role of these interactions in Ca...

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Bibliografiske detaljer
Main Authors: Lynch, K. L., Gerona, R.R.L., Larsen, E. C., Marcia, R. F., Mitchell, J. C., Martin, T.F.J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096586/
https://ncbi.nlm.nih.gov/pubmed/17914059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0368
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